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发布于:2019-5-22 06:37:54  访问:22 次 回复:0 篇
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Http://www.biomedcentral.com/1471-2377/11/Page six ofFigure 3 The pictures show minimum
Of the 59 MS patients participating in the study, 56 were on disease-modifying therapy.Scan-rescan datasetICC was slightly higher for the post-contrast SWI segmentation VVV measures than for the pre-contrast measures (Table 2). All VVV measures showed high ICC values and were significant (p < .003). The highest ICC were shown for the ATVV (.0.891) with vein sizes > .six mm Rences (P < 0.05)in use [31]. In the present study, the housing comparison getting most reproducible. The VIF and DFV ICC values ranged between 0.738 and 0.815.CCSVI status assessmentResultsDemographic and clinical characteristicsTable 1 shows demographic, clinical and conventional MRI qualities of MS pati.Http://www.biomedcentral.com/1471-2377/11/Page 6 ofFigure 3 The photos display minimum projection (mIP) (horizontal upper row), apparent total venous volume (ATVV) (horizontal middle upper row), ATVV using a diameter < .3 mm (horizontal middle lower row) and average distance from voxel (DFV) map (horizontal lower row) for a healthy control (HC) (vertical left column), relapsing-remitting PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/26162776 (RR) (vertical middle column) and secondary progressive (SP) (vertical proper column) many sclerosis patients. The photos of ATVV and ATVV using a diameter < .3 mm display the differences between HC, RR and SP MS patients [please note decreased ATVV (represented in light blue for ATVV and light green for ATVV with a diameter < .3 mm)] especially in the ventricular, periventricular white matter, deep gray matter and cortical structures between HC and MS patients, but no difference between RR and SP MS patients. The DFV maps show the differences between HC, RR and SP MS patients (please note that the green color represents distance closer to the veins, whereas the yellow and orange colors represent longer distance to the veins). RR and SP MS show more yellow and orange color compared to HC.Zivadinov et al. BMC Neurology 2011, 11:128 http://www.biomedcentral.com/1471-2377/11/Page 7 ofFigure 4 Contrast enhanced susceptibility weighted imaging (SWI) increases detection of signal hypointensities on SWI venography in patient with multiple sclerosis, in T2 lesions and normal appearing white matter [30]. Presented are pre-contrast (left), single dose postcontrast (middle) and triple dose post-contrast (right) images. The rows represent: a) high-pass filtered SWI, b) SWI phase mask, c) magnitude image multiplied 6 times by the phase mask, and d) minimum Intensity Projection image over 13 slices. Larger number and better defined signal hypointesities are detected with single and triple dose post-contrast SWI compared to pre-contrast SWI.Zivadinov et al. BMC Neurology 2011, 11:128 http://www.biomedcentral.com/1471-2377/11/Page 8 ofpre- and post-contrast SWI VVV measures in individual MS patients were assessed using the Wilcoxon signed rank test. Correlation analysis between severity of CCSVI (VHISS) and pre- and post-contrast VVV parameters was performed using the Spearman rank correlation coefficient. The primary null hypothesis was that there is no association between CCSVI and MRI brain parenchyma vein pathology. As a robust test of the hypothesis that does not assume a relationship between CCSVI and brain parenchyma vein pathology, we examined PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26780312 variations in MRI variables in the complete cohort of subjects with and with out CCSVI. If significance was located, we performed the same comparison in individual diagnostic subgroups and MS disease subtypes. As a result of many comparisons, only a nominal two-tailed p-value < .01 was considered statistically significant.cohort.
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